Puretrex 5-MTHF Complex supplement pouch displayed on a light marble surface with spinach, broccoli, avocado slices, and seeds around it.
5-MTHF Complex with Quatrefolic® - ingredients and dosage information
5-MTHF Complex with Quatrefolic® - who is this supplement for
5-MTHF Complex with Quatrefolic® - directions for use
5-MTHF Complex with Quatrefolic® - quality and trust certifications
5-MTHF Complex with Quatrefolic® - back of packaging with supplement facts
5-MTHF Complex with Quatrefolic® - additional product details
Letterbox-friendly packaging ensuring fast delivery straight to your mailbox without the need to wait at home or collect the parcel
Supplement Facts for PURETREX 5-MTHF Complex showing dosage, ingredients, and nutritional values of active folate, Vitamin B6, and Vitamin B12
PURETREX 5-MTHF Complex supplement pouch with Quatrefolic active folate, Vitamin B9 and B12, 5mg advanced formula for energy, focus, and support

5-MTHF Complex

5.0 from 11 reviews

Quatrefolic® folate with vitamins B12, B6 and B2, niacin, pantothenic acid and biotin, in a vegan capsule.

  • 120 capsules
  • 1 a day
  • 120-day supply
  • Vitamin B12 contributes to the reduction of tiredness and fatigue.
  • Vegan capsule shell made from pullulan.
Quantity

Free UK delivery on orders over £50 with Royal Mail Tracked 48. Order by 1pm Monday to Friday and it ships the same day. UK delivery in 1–4 business days.

Ingredients & nutrition information

Nutrition information

Serving size: 1 capsule · 120 servings per pouch

Ingredient Per 1 capsule%NRV
Vitamin B12 (as methylcobalamin) 1mg (1,000µg)40,000%
Vitamin B6 (as pyridoxal-5-phosphate) 20mg1,429%
Vitamin B2 (as riboflavin-5-phosphate) 20mg1,429%
Niacin (as nicotinamide) 50mg313%
Pantothenic Acid (vitamin B5, as calcium pantothenate) 50mg833%
Biotin 1,000µg2,000%
Organic Spirulina Powder 150mg–
Organic Beetroot Powder 100mg–

Also contains 5-MTHF (Quatrefolic®). Other ingredients: pullulan (vegan capsule shell). NRV = Nutrient Reference Value. Made in a facility that does not process common allergens such as milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy or sesame. Net weight 72g.

Directions & warnings

Directions: take 1 capsule daily with water, preferably with a meal, or as directed by a healthcare professional. Do not exceed the recommended daily dose.

Warnings: food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, or taking medication, consult your doctor before use. Not intended for use by children under 18. Keep out of reach of young children.

Storage: store in a cool, dry place, away from direct sunlight.

WHAT'S INSIDE

Every ingredient. What it is.

Tap an ingredient to see what it is. Amounts are per daily dose, as printed on the label.

Full ingredients panel
5-MTHF 5-MTHFQuatrefolic®
What it is

(6S)-5-methyltetrahydrofolate, a form of folate, as the branded glucosamine salt Quatrefolic®. Folate contributes to normal psychological function.

Vitamin B12 Vitamin B121,000 µg · 40,000% NRV
What it is

Methylcobalamin, a form of vitamin B12. Vitamin B12 contributes to normal red blood cell formation.

Vitamin B6 Vitamin B620 mg · 1,429% NRV
What it is

Pyridoxal-5-phosphate (P-5-P), a form of vitamin B6. Vitamin B6 contributes to normal protein and glycogen metabolism.

Vitamin B2 Vitamin B220 mg · 1,429% NRV
What it is

Riboflavin-5-phosphate, a form of riboflavin. Riboflavin contributes to the maintenance of normal vision.

Niacin Niacin50 mg · 313% NRV
What it is

Nicotinamide, a form of vitamin B3. Niacin contributes to the maintenance of normal skin.

Pantothenic Acid Pantothenic Acid50 mg · 833% NRV
What it is

Vitamin B5, here as calcium pantothenate. Pantothenic acid contributes to normal mental performance.

Biotin Biotin1,000 µg · 2,000% NRV
What it is

Also called vitamin B7. Biotin contributes to the maintenance of normal hair.

Spirulina Spirulina150 mg · organic
What it is

A blue-green alga, dried and ground to a powder.

Beetroot Beetroot100 mg · organic
What it is

Beetroot, dried and ground to a powder.

Vegan Non-GMO Allergen-free facility

BEFORE YOU BUY ANY FOLATE SUPPLEMENT

Check the label first

WHAT TO CHECKPURETREX
Folate form statedQuatrefolic® 5-MTHF
B12 form statedMethylcobalamin
Proprietary blendNone

30-day money-back guarantee

Not for you? Email support@puretrex.co.uk within 30 days of receiving your order and send it back. We refund you within 3–5 business days of receiving it. Return postage is yours unless the item is faulty, damaged or incorrect.

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100K+
Customers served
10,000+
Reviews across all channels
4.8/5
Average rating
  • The natural composition of the vitamins allows for better absorption into the body.
  • I've noticed less brain fog and clearer thinking, so all in all I'm happy with this product
  • Works great and after over a month I finally can see some changes
  • 5 stars: 11 (100%)
  • 4 stars: 0 (0%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
A
Anonymous
My favorite company to get vitamins that my body

My favorite company to get vitamins that my body needs and I see a great difference straight away especially the vitamin d!

A
Anonymous
Only just started taking but optimistic

Only just started taking but optimistic.

A
Anonymous
Great!

Great composition for lowering himocysteine level. Works great and after over a month I finally can see some changes, what was impossible with other brands.

A
Aneta Kocjan
I highly recommend purchasing this supplement

I highly recommend purchasing this supplement. The natural composition of the vitamins allows for better absorption into the body. I have problems with venous thrombosis, which means I have difficulty absorbing vitamin B12 and folic acid from food. I also have poor blood oxygenation and joint mobility issues. This vitamin complex has improved my blood circulation and joint mobility.

A
Anonymous
Very good product

Very good product, good ingredients. I recommend it.

A
Anonymous
Great company to order from

Great company to order from. Had a slight hicup due a Royal Mail error . The customer service was second to none and resolved very quickly. The products its self are top notch. Will definitely be ordering again.

Jamie

South wales

H
Hannah Davies
Clean product which wasn’t easy to find

Clean product which wasn’t easy to find. Hoping it has benefits for me

L
Lingyun
A neuroscientist recommended this...

A neuroscientist recommended this product to me, and I can feel the difference between when I'm taking it and when I'm not. I've been consistently taking it for a month now, with great results.

C
Craig
I'm trying to do...

I'm trying to do a mental reset to cut back on mindless scrolling and give my brain a jump start. I've been taking this for two months, and I've noticed less brain fog and clearer thinking, so all in all I'm happy with this product

A
Ahmed
I read here that...

I read here that this helps with optimal cognitive function, so I've been taking it in combination with lion's mane. I've noticed that I've been more focused and sharp, and I'm looking forward to seeing the longer-term results.

s
sam
i like it

i like it very much.

DIRECTIONS

Simple enough to stick

A capsule on a kitchen counter next to a glass of green smoothie
  • 1 Take it with a meal

    One capsule with water, preferably at a meal.

  • 2 Pick one meal

    Breakfast or dinner, whichever is easier to remember.

SUITABILITY

Made for your routine

A woman making a green smoothie in a bright kitchen

Great fit if you

  • Want folate and B vitamins in one daily capsule
  • Would rather reorder every few months than every few weeks

Not for you if you

  • Are under 18.
  • Are pregnant, breastfeeding or taking medication, unless your doctor has said yes first.

QUESTIONS

Before you order

What is Quatrefolic®?

Quatrefolic® is a branded form of 5-MTHF, (6S)-5-methyltetrahydrofolate, supplied as a glucosamine salt. Many supplements use folic acid, a synthetic form of folate. 5-MTHF is the main form of folate found in the blood.

How is this different from the Liposomal B12 Complex Drops?

The drops give 5,000 µg of vitamin B12 in three forms, with 400 µg of folate as L-methylfolate, in a liquid taken under the tongue. This capsule is built around Quatrefolic® folate, with 1,000 µg of B12 and vitamins B2, B6, niacin, pantothenic acid and biotin.

What if I miss a day?

Take your usual capsule the next day. Do not double up to make up for it.

How do I cancel my subscription?

Log in to your account, open Subscriptions and cancel in a few clicks. You can also pause, skip or change the frequency there. If you get stuck, email support@puretrex.co.uk or call 0125 9231 234 and we will do it for you.

PAIRS WELL WITH

Complete the routine

  • Liposomal Vitamin C
    Liposomal Vitamin C £30.00 1 softgel a day
    Why add it

    Vitamin C contributes to the protection of cells from oxidative stress. 1,000 mg of vitamin C in one softgel a day.